Licenses Offered | Epsilon Molecular Engineering Co., Ltd.

1. EME's Linker Technology

cnvK puromycin linker

EME utilizes its proprietary cnvK linker in its screening technology, enabling it to screen candidate clones from a vast library in a short period of time.

In the cDNA display method, the puromycin linker, a key technology for genotype-phenotype mapping, utilizes EME's proprietary cnvK linker. By irradiating the cnvK linker with mRNA hybridized at a specific site using UV light, rapid linking occurs via photocrosslinking, forming an mRNA-cnvK linker complex. This significantly reduces the time required for the entire cDNA display molecule preparation process.

2. Usage record by academics and professors.

Case Study 1

Megascale analysis of protein folding stability published in Nature.

(University of Tokyo, Northwestern University, etc.)

Reference paper

https://www.nature.com/articles/s41586-023-06328-6

Case Study 2

Development of the world's smallest and fastest enzyme selection system, "SMART method"

(Tokyo University of Science, Nagoya University, Saitama University)

Reference paper

https://pubs.acs.org/doi/10.1021/acssynbio.5c00968

Case Study 3

Applications of transglutaminase substrate screening and comprehensive profiling

(Nagoya University, Saitama University, etc.)

Reference paper

3. Regarding the paid provision of the cnvK linker

We can provide this product to academics as a research reagent for a fee. For researchers at companies, we will first enter into a license agreement, and we will also provide it for a fee with limited use as appropriate.
For any of these services, disclosure of the intended use is required. Please contact us for details.

Request an inquiry regarding the cnvK linker.

Various license provision

1. EME's Linker Technology

cnvK puromycin linker

2. Usage record by academics and professors.

3. Regarding the paid provision of the cnvK linker